The greatest potential benefit of interim FDG PET/CT evaluation is the potential to inform "response-adapted therapy," whereby treatment could be de-escalated in intensity in the setting of a satisfactory early response or escalated if early response is inadequate.4
4. Imaging for Staging and Response Assessment in Lymphoma. Sarah A. Johnson , Anita Kumar, Matthew J. Matasar, Heiko Schöder, Jürgen Rademaker. Published Online:Jul 23 2015https://doi.org/10.1148/radiol.2015142088. https://pubs.rsna.org/doi/full/10.1148/radiol.2015142088